2000年以色列西尼罗河热疫情：流行病学方面
West Nile fever outbreak, Israel, 2000: epidemiologic aspects.
作者信息
Weinberger M, Pitlik S D, Gandacu D, Lang R, Nassar F, Ben David D, Rubinstein E, Izthaki A, Mishal J, Kitzes R, Siegman-Igra Y, Giladi M, Pick N, Mendelson E, Bin H, Shohat T
机构信息
Internal Medicine C & Infectious Diseases, Rabin Medical Center, Beilinson Campus, Petach-Tikva 49100, Israel.
出版信息
Emerg Infect Dis. 2001 Jul-Aug;7(4):686-91. doi: 10.3201/eid0704.010416.
From August 1 to October 31, 2000, 417 cases of West Nile (WN) fever were serologically confirmed throughout Israel; 326 (78%) were hospitalized patients. Cases were distributed throughout the country; the highest incidence was in central Israel, the most populated part. Men and women were equally affected, and their mean age was 54+/-23.8 years (range 6 months to 95 years). Incidence per 1,000 population increased from 0.01 in the 1st decade of life to 0.87 in the 9th decade. There were 35 deaths (case-fatality rate 8.4%), all in patients >50 years of age. Age-specific case-fatality rate increased with age. Central nervous system involvement occurred in 170 (73%) of 233 hospitalized patients. The countrywide spread, number of hospitalizations, severity of the disease, and high death rate contrast with previously reported outbreaks in Israel.
2000年8月1日至10月31日期间，以色列各地经血清学确诊的西尼罗河热病例有417例；其中326例（78%）为住院患者。病例分布于全国各地；发病率最高的是以色列中部人口最密集的地区。男性和女性受影响程度相同，平均年龄为54±23.8岁（年龄范围6个月至95岁）。每千人口发病率从生命的第一个十年的0.01增至第九个十年的0.87。有35例死亡（病死率8.4%），均为年龄超过50岁的患者。年龄特异性病死率随年龄增长而升高。233例住院患者中有170例（73%）出现中枢神经系统受累情况。此次疫情在全国范围内的传播、住院人数、疾病严重程度以及高死亡率与以色列此前报告的疫情形成了对比。
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