Belkina L M, Saltykova V A, Pshennikova M G
Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow.
Bull Exp Biol Med. 2001 Jun;131(6):529-32. doi: 10.1023/a:1012386115427.
In intact August rats, the cardiac contractile function at rest was by 76% higher than in Wistar rats, while their hearts, both intact and after acute myocardial infarction, were more resistant to isometric load than the hearts of Wistar rats. Postinfarction mortality in August rats was 18% vs. 70% in Wistar rats. Adrenoreactivity of the myocardium in August rats was decreased compared to that in Wistar rats. These peculiarities can determine high resistance of August rats to myocardial infarction.
在完整的奥古斯特大鼠中，静息时的心脏收缩功能比Wistar大鼠高76%，而它们完整的心脏以及急性心肌梗死后的心脏，比Wistar大鼠的心脏对等长负荷更具抵抗力。奥古斯特大鼠梗死后的死亡率为18%，而Wistar大鼠为70%。与Wistar大鼠相比，奥古斯特大鼠心肌的肾上腺素反应性降低。这些特性可决定奥古斯特大鼠对心肌梗死的高抵抗力。
