Zdobnov E M, Apweiler R
EMBL Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
Bioinformatics. 2001 Sep;17(9):847-8. doi: 10.1093/bioinformatics/17.9.847.
InterProScan is a tool that scans given protein sequences against the protein signatures of the InterPro member databases, currently--PROSITE, PRINTS, Pfam, ProDom and SMART. The number of signature databases and their associated scanning tools as well as the further refinement procedures make the problem complex. InterProScan is designed to be a scalable and extensible system with a robust internal architecture.
The Perl-based InterProScan implementation is available from the EBI ftp server (ftp://ftp.ebi.ac.uk/pub/software/unix/iprscan/) and the SRS-basedInterProScan is available upon request. We provide the public web interface (http://www.ebi.ac.uk/interpro/scan.html) as well as email submission server (interproscan@ebi.ac.uk).
InterProScan是一种工具,可针对InterPro成员数据库(目前为PROSITE、PRINTS、Pfam、ProDom和SMART)的蛋白质特征扫描给定的蛋白质序列。特征数据库的数量及其相关的扫描工具以及进一步的细化程序使得问题变得复杂。InterProScan被设计为一个具有强大内部架构的可扩展系统。
基于Perl的InterProScan实现可从EBI ftp服务器(ftp://ftp.ebi.ac.uk/pub/software/unix/iprscan/)获取,基于SRS的InterProScan可根据请求提供。我们提供公共网页界面(http://www.ebi.ac.uk/interpro/scan.html)以及电子邮件提交服务器(interproscan@ebi.ac.uk)。