萘衍生物：一类新型的选择性环氧化酶-2抑制剂。
Naphthalene derivatives: A new series of selective cyclooxygenase-2 inhibitors.
作者信息
Feixas J, Jiménez J M, Godessart N, Puig C, Soca L, Crespo M I
机构信息
Almirall Prodesfarma, Research Center, Cardener 68-74, 08024, Barcelona, Spain.
出版信息
Bioorg Med Chem Lett. 2001 Oct 22;11(20):2687-90. doi: 10.1016/s0960-894x(01)00534-0.
Abstract
A new series of potent and selective cyclooxygenase-2 inhibitors have been prepared. Some of these compounds show good oral anti-inflammatory activity in rats.
摘要
已经制备了一系列新的强效且选择性的环氧化酶-2抑制剂。其中一些化合物在大鼠中显示出良好的口服抗炎活性。
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