Maeshima S, Ozaki F, Okita R, Yamaga H, Okada H, Kakishita K, Moriwaki H, Roger P
Department of Neurological Surgery, Hidaka General Hospital, Japan.
Brain Inj. 2001 Oct;15(10):927-33. doi: 10.1080/02699050110065646.
A 45-year-old right-handed woman suffered transient aphasia and persistent amnesia after a right thalamic haemorrhage. This patient appeared to have crossed aphasia, although it disappeared within 8 weeks. It is noteworthy that the patient had a unilateral right thalamic lesion but exhibited both verbal and non-verbal memory impairment. Computed tomography and magnetic resonance imaging revealed cerebral haemorrhage in the right thalamus involving the ventral anterior nucleus, medioventral nucleus, mamillothalamic tract, internal medullary lamina, and mediodorsal nucleus. An amytal test was performed and suggested that the right hemisphere was dominant for language functions and the left hemisphere was dominant for visuospatial functions. Single photon emission CT revealed a low perfusion area only in the right thalamus. These findings suggest that the right hemisphere might be dominant for both verbal and non-verbal memory function in this patient, although visuospatial function was lateralized in the left hemisphere.
一名45岁右利手女性在右侧丘脑出血后出现短暂性失语和持续性失忆。该患者似乎存在交叉性失语,不过在8周内消失了。值得注意的是,患者有单侧右侧丘脑病变,但同时出现了言语和非言语记忆障碍。计算机断层扫描和磁共振成像显示右侧丘脑脑出血,累及腹前核、内侧腹核、乳头丘脑束、内髓板和背内侧核。进行了阿米妥试验,结果提示右侧半球在语言功能方面占优势,左侧半球在视觉空间功能方面占优势。单光子发射计算机断层扫描显示仅右侧丘脑存在低灌注区。这些发现表明,尽管视觉空间功能定位于左侧半球,但在该患者中右侧半球可能在言语和非言语记忆功能方面均占优势。