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[左侧丘脑梗死所致失忆、虚构及非失语性错名]

[Amnesia, confabulation and nonaphasic misnaming after left thalamic infarct].

作者信息

Hayashi Ryuichiro, Ohashi Masashi, Watanabe Ryo, Mimura Masaru, Katsumata Yasushi

机构信息

Department of Neurology, Yokohama City Hospital, 56 Okasawa-cho, Hodogaya-ku, Yokohama 240-8555, Japan.

出版信息

No To Shinkei. 2003 Jun;55(6):530-5.

Abstract

A 72-year-old right handed woman developed amnesia, confabulation and abnormal (bizarre) verbal response after the left thalamic infarction. Clinical features including disorientation, euphoria and various kinds of paraphasia coincided in nonaphasic misnaming. MR images showed that lesions involved the genu of the internal capsule, the anteroventral nucleus, the lateroventral nucleus, intralaminar nuclei, the mamillothalamic tract and the region around the ventral thalamus. 99mTc-HMPAO-SPECT revealed decreased uptake in the left frontal lobe, probably due to the disconnection from the thalamus. These findings suggest that the dysfunction of the thalamus (mainly ventrolateral) and the left frontal lobe caused the disturbance of the self-monitoring in the language use, which generated confabulation and nonaphasic misnaming in our case.

摘要

一名72岁右利手女性在左侧丘脑梗死之后出现失忆、虚构及异常(怪异)言语反应。临床特征包括定向障碍、欣快及各种错语症,这些在非失语性错名中同时出现。磁共振成像显示病灶累及内囊膝部、前腹侧核、外侧腹侧核、板内核、乳头丘脑束及丘脑腹侧周围区域。99m锝-六甲基丙二胺肟单光子发射计算机断层扫描显示左侧额叶摄取减少,这可能是由于与丘脑的联系中断所致。这些发现提示丘脑(主要是腹外侧)及左侧额叶功能障碍导致语言使用中自我监测功能紊乱,从而在我们的病例中产生了虚构及非失语性错名。

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