Fleischman A I, Justice D, Bierenbaum M L, Stier A, Sullivan A
J Nutr. 1975 Oct;105(10):1286-90. doi: 10.1093/jn/105.10.1286.
The effect of increasing dietary linoleate upon in vivo platelet aggregation and disaggregation in 20 males and 46 female adult humans was studied. In creasing exogenous linoleate for 2 weeks from 2.89 +/- 0.11 to 5.00 +/- 0.26% of energy was associated with the doubling of the aggregation time and halving of the disaggregation time. Decreasing dietary linoleate in the following 2-week feeding period was associated with a reversal of the effect.