Kinsella J E, Hwang D H, Yu P, Mai J, Shimp J
Biochem J. 1979 Dec 15;184(3):701-4. doi: 10.1042/bj1840701.
Feeding trans,trans-9,12-linoleate to rats as 50 and 100% of the dietary fat decreased the concentrations of n-6 fatty acids, i.e. 18:2, 20:3 and 20:4, in heart, kidney, lung, adipose tissue and platelets of rats. The concentrations of prostaglandin products prostaglandins E1, E2 and F2 alpha in serum were significantly decreased in rats receiving high concentrations of dietary trans, trans-linoleate.
给大鼠喂食反式、反式-9,12-亚油酸,其占膳食脂肪的比例分别为50%和100%,可降低大鼠心脏、肾脏、肺、脂肪组织和血小板中n-6脂肪酸(即18:2、20:3和20:4)的浓度。在摄入高浓度膳食反式亚油酸的大鼠中,血清中前列腺素产物前列腺素E1、E2和F2α的浓度显著降低。