[山野豌豆化学成分的研究]

[Studies on the chemical constitutens of Vicia amoena Fisch].

作者信息

Wei F, Yan W M

机构信息

Shenzhen Institute of Drug Control and Evaluation, Shenzhen 518029.

出版信息

Yao Xue Xue Bao. 1997 Oct;32(10):765-8.

PMID:11596220

Abstract

One new flavonoide was isolated from Vicia amoena Fisch. On the basis of spectral (UV, MS, NMR) and chemical reactions, it was elucidated to be kaempferol-3-O-beta-D-mannoside, named amoenin(A3). Moreover, five known compounds have been isolated and identified as quercetin, kaempferol, quercetin-3-O-alpha-L-rhamoside, quercetin-3-O-beta-D-glucoside, kaempferol-3, 7-O-alpha-L-dirhamoside. The total flavonoides showed significant effects on inducing hyperlipidemia and increasing micro-blood vessel elasticity.

摘要

从山野豌豆中分离出一种新的黄酮类化合物。基于光谱（紫外、质谱、核磁共振）和化学反应，确定其为山柰酚-3-O-β-D-甘露糖苷，命名为山野豌豆苷（A3）。此外，还分离鉴定出5种已知化合物，分别为槲皮素、山柰酚、槲皮素-3-O-α-L-鼠李糖苷、槲皮素-3-O-β-D-葡萄糖苷、山柰酚-3,7-O-α-L-二鼠李糖苷。总黄酮类化合物对诱导高脂血症和增加微血管弹性有显著作用。