[仙鹤草中黄酮类化合物的分离与鉴定研究]

[Studies on isolation and identification of flavonoids in herbs of Agrimonia pilosa].

作者信息

Pan Ya, Liu Hong-Xia, Zhuang Yu-Lei, Ding Li-Qin, Chen Li-Xia, Qiu Feng

机构信息

School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2008 Dec;33(24):2925-8.

PMID:19294852

Abstract

OBJECTIVE

To study the chemical constituents in Agrimonia pilosa.

METHOD

The compounds were isolated and purified by various column chromatographic methods and elucidated on the basis of chemical and spectroscopic evidences.

RESULT

Nine flavonoids were obtained and identified as tiliroside (1), kaempferol 3-O-alpha-L-rhampyranoside (2), quercetin 3-O-alpha-L-rhampyranoside (3), quercetin 3-O-beta-D-glucopyranoside (4), kaempferol 3-O-beta-D-glucopyranoside (5), kaempferol (6), apigenin (7), luteolin (8), quercetin (9).

CONCLUSION

Compounds 1-3, 5, 6 and 8 were isolated from this plant for the first time.

摘要

目的

研究龙牙草中的化学成分。

方法

采用多种柱色谱方法对化合物进行分离纯化，并根据化学和光谱证据进行鉴定。

结果

得到9种黄酮类化合物，分别鉴定为椴树苷（1）、山柰酚3 - O - α - L - 鼠李糖苷（2）、槲皮素3 - O - α - L - 鼠李糖苷（3）、槲皮素3 - O - β - D - 葡萄糖苷（4）、山柰酚3 - O - β - D - 葡萄糖苷（5）、山柰酚（6）、芹菜素（7）、木犀草素（8）、槲皮素（9）。