来自显脉虎皮楠的抗氧化黄酮苷。

Antioxidant flavonoid glycosides from Daphniphyllum calycinum.

作者信息

Gamez E J, Luyengi L, Lee S K, Zhu L F, Zhou B N, Fong H H, Pezzuto J M, Kinghorn A D

机构信息

Program for Collaborative Research in the Pharmaceutical Sciences and Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, USA.

出版信息

J Nat Prod. 1998 May;61(5):706-8. doi: 10.1021/np9800203.

DOI:10.1021/np9800203

PMID:9599286

Abstract

A novel flavonoid diglycoside, 5,6,7,4'-tetrahydroxyflavonol 3-O-rutinoside (1), and a previously known compound, kaempferol 3-O-neohesperidoside (2), were isolated from an ethyl acetate extract of Daphniphyllum calycinum leaves that showed significant activity in a 1,1-diphenyl-2-picrylhydrazyl (DPPH) free-radical assay. The structure of 1 was elucidated by a combination of spectroscopic methods, and compounds 1 and 2 were found to be moderately active as antioxidants in the DPPH assay.

摘要

从显苞虎皮楠（Daphniphyllum calycinum）叶的乙酸乙酯提取物中分离得到一种新型黄酮二糖苷，5,6,7,4'-四羟基黄酮醇3-O-芸香糖苷（1）和一种已知化合物山柰酚3-O-新橙皮糖苷（2），该提取物在1,1-二苯基-2-苦基肼（DPPH）自由基测定中显示出显著活性。通过光谱方法相结合阐明了1的结构，并且发现化合物1和2在DPPH测定中作为抗氧化剂具有中等活性。