Hong Y F, Han G Y, Guo X M
Research Laboratory of Natural and Synthetic Drugs, College of Pharmacy, Second Military Medical University, Shanghai 200433.
Yao Xue Xue Bao. 1997 Jun;32(6):473-5.
Xilingzhimu, the rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae), has been prescribed as antipyretic, anti-inflammatory, diuretic and hypoglycemic agents in Chinese traditional medicine. In this paper, two xanthone glycosides I and II, were isolated from Xilingzhimu by conventional method. The structures of I and II were identified on the basis of chemical reactions and UV, IR, 1HNMR, 13CNMR and DEPT. Compound I was identified as mangiferin and II is a new compound, named neomangiferin. Its structure is 7-O-beta-D-glucopyranosyl-mangiferin.
知母为百合科植物知母(Anemarrhena asphodeloides Bunge)的根茎,在传统中药中被用作解热、抗炎、利尿和降血糖药物。本文采用常规方法从知母中分离得到两种氧杂蒽酮糖苷I和II。通过化学反应以及紫外光谱(UV)、红外光谱(IR)、核磁共振氢谱(1HNMR)、核磁共振碳谱(13CNMR)和无畸变极化转移增强法(DEPT)对I和II的结构进行了鉴定。化合物I被鉴定为芒果苷,化合物II是一种新化合物,命名为新芒果苷。其结构为7 - O - β - D - 吡喃葡萄糖基芒果苷。