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[胡黄连根中的苯乙醇苷类成分]

[Phenylethanoid glycosides from root of Picrorhiza scrophulariiflora].

作者信息

Wang Hao, Ye Wen-Cai, Xiong Fei, Zhao Shou-Xun

机构信息

Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2004 Jun;29(6):531-4.

Abstract

OBJECTIVE

To study the phenylethanoid glycosides from root of Picrorhiza scrophulariiflora.

METHOD

Column chromatographic techniques were used for isolation and purification of chemical constituents of the plant and the structures were identified by spectroscopic analysis.

RESULT

Six phenylethanoid glycosides were isolated and elucidated as: 2-(3,4-dihydroxyphenyl)-ethyl-O-beta-D-glucopyranoside (1), 2-(3-hydroxy-4-methoxyphenyl)-ethyl-O-beta-D-glucopyranosyl (1-->3) beta-D-glucopyranoside (2), scroside B (3), hemiphroside A (4), plantainoside D (5) and scroside A (6), respectively.

CONCLUSION

Compounds 1, 2, 4 and 5 were isolated from this plant for the first time and compound 2 was firstly obtained from natural source.

摘要

目的

研究胡黄连根中的苯乙醇苷类成分。

方法

采用柱色谱技术对该植物的化学成分进行分离纯化,并通过光谱分析鉴定其结构。

结果

分离得到6个苯乙醇苷类成分,分别鉴定为:2-(3,4-二羟基苯基)乙基-O-β-D-吡喃葡萄糖苷(1)、2-(3-羟基-4-甲氧基苯基)乙基-O-β-D-吡喃葡萄糖基(1→3)β-D-吡喃葡萄糖苷(2)、胡黄连苷B(3)、半枝莲苷A(4)、车前苷D(5)和胡黄连苷A(6)。

结论

化合物1、2、4和5为首次从该植物中分离得到,化合物2为首次从天然来源获得。

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