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重度脱垂合并隐匿性压力性尿失禁女性患者的泌尿生殖系统联合脱垂修复及预防性无张力阴道吊带术:初步结果

Combined genitourinary prolapse repair and prophylactic tension-free vaginal tape in women with severe prolapse and occult stress urinary incontinence: preliminary results.

作者信息

Gordon D, Gold R S, Pauzner D, Lessing J B, Groutz A

机构信息

Urogynecology and Pelvic Floor Unit, Department of Obstetrics and Gynecology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv University Sackler Faculty of Medicine, Tel Aviv, Israel.

出版信息

Urology. 2001 Oct;58(4):547-50. doi: 10.1016/s0090-4295(01)01327-9.

Abstract

OBJECTIVES

Continent patients with a positive stress test demonstrated on repositioning of severe genitourinary prolapse are considered to be at high risk of developing postoperative symptomatic stress urinary incontinence (SUI). Our aim was to evaluate in a prospective study whether a prophylactic, tension-free vaginal tape (TVT) procedure, performed during prolapse repair, may prevent the development of postoperative SUI in these women.

METHODS

Thirty consecutive, clinically continent women (mean age 64.5 +/- 9.04 years) with severe genitourinary prolapse and occult SUI were prospectively enrolled. Occult SUI was defined as a positive stress test with repositioning of the prolapse during the preoperative urodynamic studies. All patients had urethral hypermobility; none had intrinsic sphincter deficiency. In addition to genitourinary prolapse repair, these patients underwent concomitant TVT to prevent postoperative SUI. Patients were followed up for at least 1 year. Repeated urodynamic studies were performed at 3 to 6 months postoperatively. The main outcome measures were postoperative SUI, persistent or de novo detrusor instability, and recurrence of prolapse.

RESULTS

The mean duration of follow-up was 14.25 +/- 3.08 months (range 12 to 24). None of the patients developed postoperative symptomatic SUI. However, three asymptomatic patients (10%) had a positive stress test during their postoperative urodynamic evaluation. Nine patients (30%) had detrusor instability before surgery, which persisted in six (66%) postoperatively. Postoperative de novo detrusor instability was diagnosed in four other patients (13.33%). None of the patients had recurrent urogenital prolapse, nor did they have clinical evidence of bladder outlet obstruction.

CONCLUSIONS

The preliminary results of TVT as a prophylactic procedure in clinically continent women with severe prolapse and occult SUI are encouraging. Long-term follow-up is required to confirm the durability of these results.

摘要

目的

在重度泌尿生殖系统脱垂复位时压力试验呈阳性的可控性患者被认为术后发生症状性压力性尿失禁(SUI)的风险较高。我们的目的是在一项前瞻性研究中评估,在脱垂修复过程中进行预防性无张力阴道吊带(TVT)手术是否可以预防这些女性术后SUI的发生。

方法

前瞻性纳入30例连续的临床可控性女性(平均年龄64.5±9.04岁),她们患有重度泌尿生殖系统脱垂和隐匿性SUI。隐匿性SUI定义为术前尿动力学研究中脱垂复位时压力试验呈阳性。所有患者均有尿道活动过度;均无内在括约肌缺陷。除了泌尿生殖系统脱垂修复外,这些患者还同时接受TVT手术以预防术后SUI。对患者进行至少1年的随访。术后3至6个月进行重复尿动力学研究。主要观察指标为术后SUI、持续性或新发逼尿肌不稳定以及脱垂复发。

结果

平均随访时间为14.25±3.08个月(范围12至24个月)。所有患者均未发生术后症状性SUI。然而,3例无症状患者(10%)在术后尿动力学评估时压力试验呈阳性。9例患者(30%)术前有逼尿肌不稳定,其中6例(66%)术后持续存在。另外4例患者(13.33%)被诊断为术后新发逼尿肌不稳定。所有患者均无泌尿生殖系统脱垂复发,也没有膀胱出口梗阻的临床证据。

结论

TVT作为一种预防性手术应用于患有重度脱垂和隐匿性SUI的临床可控性女性的初步结果令人鼓舞。需要长期随访以证实这些结果的持久性。

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