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在无症状尿失禁的阴道脱垂手术患者中,基本办公评估和尿动力学期间可明确的应激性尿失禁的预测价值。

The predictive value of demonstrable stress incontinence during basic office evaluation and urodynamics in women without symptomatic urinary incontinence undergoing vaginal prolapse surgery.

机构信息

Department of Obstetrics and Gynaecology, Martini Hospital, Groningen, The Netherlands.

Department of Obstetrics and Gynaecology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

出版信息

Neurourol Urodyn. 2018 Mar;37(3):1011-1018. doi: 10.1002/nau.23384. Epub 2017 Aug 23.

Abstract

AIMS

Women with pelvic organ prolapse without symptoms of urinary incontinence (UI) might demonstrate stress urinary incontinence (SUI) with or without prolapse reduction. We aimed to determine the value of demonstrable SUI during basic office evaluation or urodynamics in predicting SUI after vaginal prolapse repair in these women.

METHODS

Women included in the CUPIDO trials without bothersome UI or UI more than once a week were eligible if they had undergone prolapse repair without incontinence surgery. The diagnostic and predictive value of demonstrable SUI was studied for postoperative SUI (POSUI). POSUI was defined as bothersome SUI at 1-year follow-up or treatment for SUI in the first postoperative year.

RESULTS

In 45% (77/173) of the included women urodynamics was performed. In 19% (32/172) SUI was demonstrated with basic office evaluation, against 29% (22/77) with urodynamics. Nine percent (16/172) developed POSUI, six women underwent surgery for de novo SUI. Women with demonstrable SUI were more at risk to face POSUI: twenty-eight percent versus five percent (Diagnostic Odds Ratio: 7; 95%CI 3-22). Urodynamics predicted one more woman having POSUI, but all women who underwent treatment for de novo SUI showed SUI during basic office evaluation. Test performance did not improved with the adding of urodynamics.

CONCLUSIONS

The predictive value of demonstrable SUI in symptomatically continent women undergoing vaginal prolapse repair is limited. Urodynamics added no value. The twenty-eight percent POSUI risk must be balanced against the increased complication risk if a prophylactic midurethral sling is considered.

摘要

目的

无尿失禁(UI)症状的盆腔器官脱垂女性可能会出现压力性尿失禁(SUI),无论是否伴有脱垂减轻。我们旨在确定在基本办公室评估或尿动力学检查中发现的可证明的 SUI 在这些女性阴道脱垂修复后预测 SUI 的价值。

方法

如果女性接受了脱垂修复而没有进行失禁手术,且无困扰性 UI 或每周 UI 超过一次,则符合 CUPIDO 试验的纳入标准。研究了可证明的 SUI 在术后压力性尿失禁(POSUI)中的诊断和预测价值。POSUI 定义为 1 年随访时出现困扰性 SUI 或术后第 1 年进行 SUI 治疗。

结果

在 173 名纳入女性中,45%(77/173)进行了尿动力学检查。在 172 名女性中,有 19%(32/172)通过基本办公室评估发现 SUI,而通过尿动力学检查发现的为 29%(22/77)。9%(16/172)发生 POSUI,6 名女性因新发 SUI 行手术治疗。有可证明 SUI 的女性发生 POSUI 的风险更高:28%对 5%(诊断优势比:7;95%CI 3-22)。尿动力学检查预测会有 1 名女性发生 POSUI,但所有因新发 SUI 而行手术治疗的女性在基本办公室评估时均出现 SUI。随着尿动力学检查的加入,测试性能并未提高。

结论

在接受阴道脱垂修复的症状性尿控女性中,可证明的 SUI 的预测价值有限。尿动力学检查没有增加价值。如果考虑预防性中尿道吊带术,28%的 POSUI 风险必须与增加的并发症风险相平衡。

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