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尿道活动过度和固有括约肌功能不全对经闭孔尿道中段吊带术治疗效果的影响:一项为期2年随访的前瞻性研究。

The role of urethral hypermobility and intrinsic sphincteric deficiency on the outcome of transobturator tape procedure: a prospective study with 2-year follow-up.

作者信息

Haliloglu Berna, Karateke Ates, Coksuer Hakan, Peker Hakan, Cam Cetin

机构信息

Division of Urogynecology, Department of Obstetrics and Gynecology, Faculty of Medicine, Maltepe University, Barbaros Mah. Dereboyu Cd. My World Starland D1-1 Blok D:101, Bati Atasehir, Istanbul, Turkey.

出版信息

Int Urogynecol J. 2010 Feb;21(2):173-8. doi: 10.1007/s00192-009-1010-y. Epub 2009 Oct 3.

Abstract

INTRODUCTION AND HYPOTHESIS

The aim of this study is to investigate the effect of intrinsic sphincter deficiency (ISD) and urethral hypermobility on the outcome of the transobturator tape (TOT).

METHODS

Sixty-five women were divided into three groups: group I, ISD with hypermobile urethra (n = 18); group II, ISD with fixed urethra (n = 16); and group III, hypermobile urethra without ISD (n = 31). Cure of stress urinary incontinence was defined if the patient had negative cough stress test. Cure and improvement rates were compared at 6, 12, and 24 months.

RESULTS

The cure and improvement rates of groups I and III were similar at 6, 12, and 24 months (96.1% vs 96.6%, 96.1% vs 96.6%, and 87.5 vs %96.4%, respectively). Group II had the lowest cure and improvement rates (68.7%, 66.7%, and 66.7%, respectively).

CONCLUSION

A lack of urethral hypermobility may be a risk factor for TOT failure.

摘要

引言与假设

本研究旨在探讨固有括约肌缺陷(ISD)及尿道活动过度对经闭孔尿道中段吊带术(TOT)疗效的影响。

方法

65名女性被分为三组:第一组,伴有尿道活动过度的ISD(n = 18);第二组,伴有固定尿道的ISD(n = 16);第三组,无ISD的尿道活动过度(n = 31)。若患者咳嗽压力试验为阴性,则定义为压力性尿失禁治愈。比较6个月、12个月和24个月时的治愈率及改善率。

结果

第一组和第三组在6个月、12个月和24个月时的治愈率及改善率相似(分别为96.1%对96.6%、96.1%对96.6%、87.5%对96.4%)。第二组的治愈率及改善率最低(分别为68.7%、66.7%和66.7%)。

结论

尿道活动过度的缺失可能是TOT失败的一个风险因素。

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