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新生儿静脉喂养期间的血浆肉碱水平。

Plasma carnitine levels during intravenous feeding of the neonate.

作者信息

Schiff D, Chan G, Seccombe D, Hahn P

出版信息

J Pediatr. 1979 Dec;95(6):1043-6. doi: 10.1016/s0022-3476(79)80306-6.

DOI:10.1016/s0022-3476(79)80306-6
PMID:115982
Abstract

The premature infant has a limited capacity for fatty acid oxidation. This study shows that solutions commonly used for intravenous feedings in the newborn infant contain no carnitine. Infants maintained on this solution have significantly lower total, free, and acylcarnitine levels as compared to when they are fed orally with expressed human milk or a proprietary formula, which is known to contain carnitine. The exogenous supply of carnitine to the premature infant may have a significant influence on the ability to stimulate optimal fatty acid oxidation.

摘要

早产儿脂肪酸氧化能力有限。本研究表明,新生儿静脉喂养常用的溶液中不含肉碱。与口服挤出的母乳或已知含有肉碱的专用配方奶相比,用这种溶液维持喂养的婴儿总肉碱、游离肉碱和酰基肉碱水平显著降低。向早产儿外源供应肉碱可能对刺激最佳脂肪酸氧化的能力有重大影响。

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Plasma carnitine levels during intravenous feeding of the neonate.新生儿静脉喂养期间的血浆肉碱水平。
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引用本文的文献

1
Randomised controlled trial of L-carnitine as a nutritional supplement in preterm infants.左旋肉碱作为早产儿营养补充剂的随机对照试验。
Arch Dis Child Fetal Neonatal Ed. 1998 May;78(3):F185-8. doi: 10.1136/fn.78.3.f185.
2
Parenteral nutrition: current status and concepts.肠外营养:现状与概念
Drugs. 1982 Apr;23(4):276-323. doi: 10.2165/00003495-198223040-00003.
3
Carnitine in human nutrition.人体营养中的肉碱。
Z Ernahrungswiss. 1982 Dec;21(4):257-65. doi: 10.1007/BF02020743.
4
Lipid metabolism in parenterally alimented neonates: carnitine blood concentrations and fat utilization.肠外营养新生儿的脂质代谢:肉碱血浓度与脂肪利用
Indian J Pediatr. 1983 Mar-Apr;50(403):161-8. doi: 10.1007/BF02821437.
5
Clinical and metabolic consequences of two regimens of total parenteral nutrition in the newborn.新生儿两种全胃肠外营养方案的临床及代谢后果
Arch Dis Child. 1983 Mar;58(3):168-75. doi: 10.1136/adc.58.3.168.
6
l-Carnitine. A preliminary review of its pharmacokinetics, and its therapeutic use in ischaemic cardiac disease and primary and secondary carnitine deficiencies in relationship to its role in fatty acid metabolism.左旋肉碱。对其药代动力学、在缺血性心脏病中的治疗应用以及与脂肪酸代谢作用相关的原发性和继发性肉碱缺乏症的初步综述。
Drugs. 1987 Jul;34(1):1-24. doi: 10.2165/00003495-198734010-00001.
7
Problems related to diet management of maternal phenylketonuria.与母体苯丙酮尿症饮食管理相关的问题
J Inherit Metab Dis. 1986;9 Suppl 2:183-201. doi: 10.1007/BF01799703.