Val-Bernal J F, Villoria F, Pérez-Expósito M A
Department of Anatomical Pathology, Marqués de Valdecilla University Hospital, University of Cantabria, Avda. Valdecilla 1, E-39008 Santander, Spain.
Ann Diagn Pathol. 2001 Oct;5(5):293-9. doi: 10.1053/adpa.2001.27920.
The synchronous occurrence of three different types of renal tumor in a patient is rare. We report a case of conventional (clear cell) renal cell carcinoma harboring metastatic foci of mammary carcinoma associated with two angiomyolipomas in the left kidney incidentally discovered at the autopsy. The patient was a 75-year-old woman, without the tuberous sclerosis complex, who had undergone left radical mastectomy and radiotherapy for an infiltrating duct carcinoma of breast 30 years before. This tumor was widely disseminated at autopsy, but the nontumorous renal parenchyma was free of metastases. To the best of our knowledge this combination of neoplasms has not been described before. This case shows the important role played by autopsy in the accurate investigation of interrelations among coexisting tumors.
一名患者同时出现三种不同类型的肾肿瘤实属罕见。我们报告一例常规(透明细胞)肾细胞癌病例,该病例伴有乳腺癌转移灶,并在尸检时偶然发现左肾有两个血管平滑肌脂肪瘤。患者为一名75岁女性,无结节性硬化症,30年前因乳腺浸润性导管癌接受了左乳根治性乳房切除术和放疗。尸检时发现该肿瘤广泛转移,但非肿瘤性肾实质未见转移。据我们所知,此前尚未有这种肿瘤组合的描述。该病例显示了尸检在准确研究共存肿瘤之间相互关系中所起的重要作用。