Huo Zhijun, Gao Yongsheng, Yu Zhiyong, Zuo Wenshu, Zhang Yanfang
Department of Breast Disease Centre, Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences People's Republic of China, Shandong, China.
Department of Pathology, Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences People's Republic of China, Shandong, China.
Int J Clin Exp Pathol. 2015 Nov 1;8(11):15417-21. eCollection 2015.
Tumor-to-tumor metastasis (TTM) is a rare phenomenon. We present a case of an invasive ductal carcinoma (IDC) of the breast metastasizing to a clear cell renal cell carcinoma (RCC). Breast cancer (BC) metastasis to the RCC is rarely reported, especially in resected kidney tumor. In several cases reported, IDC was the exclusively histologic type of BC metastasized to RCC. It seems that the different molecular type of IDC doesn't affect the metastatic tendencies to RCC. TTM was an indicator of diffuse disease. For any patient with a history of breast cancer, especially with multi-organs metastasis, resection of kidney tumor should be carefully considered.
肿瘤-to-肿瘤转移(TTM)是一种罕见现象。我们报告一例乳腺浸润性导管癌(IDC)转移至透明细胞肾细胞癌(RCC)的病例。乳腺癌(BC)转移至RCC鲜有报道,尤其是在切除的肾肿瘤中。在已报道的几例病例中,IDC是转移至RCC的BC唯一的组织学类型。似乎IDC不同的分子类型并不影响其向RCC转移的倾向。TTM是疾病播散的一个指标。对于任何有乳腺癌病史的患者,尤其是有多器官转移的患者,应谨慎考虑肾肿瘤切除术。