同一肾脏中同时出现三种不同组织学类型的原发性肿瘤，并伴有同侧肾上腺腺瘤：首例病例报告。

Concurrent occurrence of three primary neoplasms with different hystotype in the same kidney, associated with an adenoma of the omolateral adrenal gland: first case report.

作者信息

Morelli Luca, Pusiol Teresa, Piscioli Irene, Larosa Michelangelo, Pozzoli Gian Luigi, Monica Bruno

机构信息

Department of Anatomic Pathology, S. Maria del Carmine Hospital, Rovereto, Italy.

出版信息

Int J Urol. 2006 Sep;13(9):1236-9. doi: 10.1111/j.1442-2042.2006.01517.x.

DOI:10.1111/j.1442-2042.2006.01517.x

PMID:16984560

Abstract

We present an unusual case of concurrent occurrence of three synchronous primary tumors in the same kidney (oncocytoma, chromophobe renal cell carcinoma, angiomyolipoma) associated to an adenoma of the omolateral adrenal gland in a patient with no evident clinical symptoms. The immunohistochemistry showed a positivity for KIT in oncocytoma and chromophobe cell carcinoma, and a weak positivity in the angiomyolipoma, only in the cells positive for HMB-45. This is the first report of this kind of presentation.

摘要

我们报告了一例罕见病例，一名无明显临床症状的患者，其同一侧肾脏同时出现了三种同步原发性肿瘤（嗜酸性细胞瘤、嫌色肾细胞癌、血管平滑肌脂肪瘤），并伴有同侧肾上腺腺瘤。免疫组化显示，嗜酸性细胞瘤和嫌色细胞癌中KIT呈阳性，血管平滑肌脂肪瘤仅在HMB - 45阳性细胞中呈弱阳性。这是此类表现的首例报告。