Han Y, Xia C, Cheng X, Xiang R, Liu H, Yan Q, Xu D
Jiangsu Provincial Institute of Materia Medica, Nanjing 210009.
Zhongguo Zhong Yao Za Zhi. 1998 Nov;23(11):680-2, 703.
To study the pharmacologically active components of Eclipta prostrata.
The components were extracted by alcohol and isolated by silica gel column and subjected to pharmacological screening.
Four compounds were isolated from E. prostrata, of which two were identified as stigmasterol and alpha-terthienyl.
alpha-Terthienyl was isolated from the plant for the first time. The EtOAc part of alcoholic extraction exhibits significant hepatoprotective activity against carbon terachloride-induced liver injury in rats.
研究墨旱莲的药理活性成分。
采用乙醇提取成分，经硅胶柱分离并进行药理筛选。
从墨旱莲中分离出4种化合物，其中2种被鉴定为豆甾醇和α-三联噻吩。
首次从该植物中分离出α-三联噻吩。乙醇提取物的乙酸乙酯部位对四氯化碳诱导的大鼠肝损伤具有显著的保肝活性。
