Sun Y, Hou S, Xue G
School of Pharmacy, West China University of Medical Sciences, Chengdu 610041.
Zhongguo Zhong Yao Za Zhi. 1998 Sep;23(9):539-41, 576.
Based on a study of Concha Ostreae, to provide some reference for the rational approach to leaching mineral drugs.
Taking the change rates of compatible leaching and value of A as targets, the compatible leaching effect of Concha Ostreae with Radix et Rhizoma Rhei Praeparata, Radix Scutellariae, Pollen Typhae and Fructus Aurantii lmmaturus was studied.
If Concha Ostreae and the above cited medicinal herbs are decocted together, the yield of extract may be reduced to a certain extent, but the target composition of Radix et Rhizoma Rhei Praeparata and Fructus Aurantii lmmaturus remains intact, only the content of Radix Scutellariae baicalin may be influenced.
The relationship of technology with preparation must be taken into consideration when making choice of the proper way to leach Concha Ostreae.
通过对牡蛎的研究，为合理选择矿物类药物的提取方法提供参考。
以配伍浸出变化率及A值为指标，研究牡蛎与酒大黄、黄芩、蒲黄、枳实的配伍浸出效果。
牡蛎与上述药材合煎，提取物得率会有一定程度降低，但酒大黄和枳实的指标成分不受影响，仅黄芩中黄芩苷含量可能受到影响。
选择牡蛎合适的提取方式时，必须考虑工艺与制剂的关系。
