拟南芥小热激蛋白不断扩展的家族以及一个包含α-晶状体蛋白结构域的新蛋白家族（Acd蛋白）。
The expanding family of Arabidopsis thaliana small heat stress proteins and a new family of proteins containing alpha-crystallin domains (Acd proteins).
作者信息
Scharf K D, Siddique M, Vierling E
机构信息
Biocenter of the Goethe University, Frankfurt/Main, Germany.
出版信息
Cell Stress Chaperones. 2001 Jul;6(3):225-37. doi: 10.1379/1466-1268(2001)006<0225:tefoat>2.0.co;2.
Abstract
Comprehensive analysis of the Arabidopsis genome revealed a total of 13 sHsps belonging to 6 classes defined on the basis of their intracellular localization and sequence relatedness plus 6 ORFs encoding proteins distantly related to the cytosolic class Cl or the plastidial class of sHsps. The complexity of the Arabidopsis sHsp family far exceeds that in any other organism investigated to date. Furthermore, we have identified a new family of ORFs encoding multidomain proteins that contain one or more regions with homology to the ACD (Acd proteins). The functions of the Acd proteins and the role of their ACDs remain to be investigated.
摘要
对拟南芥基因组的全面分析显示，共有13个小分子热激蛋白（sHsps），它们基于细胞内定位和序列相关性被分为6类，另外还有6个开放阅读框（ORFs），其编码的蛋白质与胞质Cl类或质体类sHsps有较远的亲缘关系。拟南芥sHsp家族的复杂性远远超过了迄今为止所研究的任何其他生物体。此外，我们还鉴定出了一个新的开放阅读框家族，其编码的多结构域蛋白包含一个或多个与ACD（Acd蛋白）具有同源性的区域。Acd蛋白的功能及其ACD结构域的作用仍有待研究。
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