Lauritzen J B
H:S Hvidovre Hospital, ortopaedkirurgisk afdeling 333.
Ugeskr Laeger. 2001 Oct 1;163(40):5496-502.
The treatment of osteoporosis-related fractures can be difficult, when secure fixation and stable osteosynthesis is obtained in frail trabecular and cortical bone. In the case of defects, bone grafting and substitutes may be needed to reinforce osteosynthesis and promote fracture healing, which may be delayed. The structural grafts may be biologically inert or osteoconductive, but also osteoinductive, and various osteoinductive growth factors and hormones could be a supplement to treatment. Several types of osteosyntheses have improved the clinical outcome, among them: sliding hip screw, neck screws, intramedullary nails with neck screw, retrograde intramedullary nails, external fixation, cannulated screws, various plates, tension band wiring, threaded K-pins, and to some extent arthroplasties and reconstructive spine instrumentation. The goal in the treatment of osteoporosis-related fractures is to restore functional abilities as soon as possible, and the prevention of subsequent fractures is indicated.
在脆弱的小梁骨和皮质骨中实现牢固固定和稳定的骨合成时，骨质疏松相关骨折的治疗可能会很困难。在存在骨缺损的情况下，可能需要植骨和骨替代物来加强骨合成并促进骨折愈合，而骨折愈合可能会延迟。结构性植骨可能是生物惰性的、骨传导性的，也可能是骨诱导性的，各种骨诱导生长因子和激素可以作为治疗的补充。几种类型的骨合成方法改善了临床结果，其中包括：滑动髋螺钉、颈螺钉、带颈螺钉的髓内钉、逆行髓内钉、外固定、空心螺钉、各种钢板、张力带钢丝、螺纹克氏针，以及在一定程度上的关节成形术和脊柱重建器械。骨质疏松相关骨折治疗的目标是尽快恢复功能能力，并预防后续骨折。
