[糖尿病血管并发症发生中的内皮功能障碍]

[Endothelial dysfunction in the development of vascular complications in diabetes mellitus].

作者信息

Dedov I I, Shestakov M V, Kochemasova T V, Severina I S, Baryshnikov A Iu

出版信息

Ross Fiziol Zh Im I M Sechenova. 2001 Aug;87(8):1073-84.

Abstract

Patients with type 1 diabetes, aged 18 to 42 years, were compared to those aged 11 to 22 years. Activities of endothelial vasoactive factors and endothelial and leukocyte adhesion molecules were studied at different stages of development diabetes complications: nephropathy and retinopathy. The findings reveal role of the vasoactive factors in microangiopathy course.

摘要

将18至42岁的1型糖尿病患者与11至22岁的患者进行了比较。在糖尿病并发症（肾病和视网膜病变）发展的不同阶段，研究了内皮血管活性因子以及内皮和白细胞粘附分子的活性。研究结果揭示了血管活性因子在微血管病变过程中的作用。