叶下珠的化学成分及其对乙型肝炎病毒的抗病毒活性
[Chemical constituents of Phyllanthus urinaria L. and its antiviral activity against hepatitis B virus].
作者信息
Zhong Y, Zuo C, Li F, Ding X, Yao Q, Wu K, Zhang Q, Wang Z, Zhou L W, Lan J, Wang X
机构信息
Institute of Meteria Medica, Shangdong Academy of Medical Sciences, Jinan 250062.
出版信息
Zhongguo Zhong Yao Za Zhi. 1998 Jun;23(6):363-4, 384.
Studies on the chemical constituents of Phyllanthus urinaria and its antiviral activity against hepatitis B virus were completed. Eleven compounds have been isolated. Two of them are new compounds methyl ester dehydrochebulic acid and methyl brevifolin carboxylate. Antiviral experiments on HBsAg in vitro and liver damage caused by CCl4 have shown that. Phyllanthus urinaria possesses antiviral activities against HBV.
完成了叶下珠化学成分及其抗乙型肝炎病毒活性的研究。已分离出11种化合物。其中两种是新化合物脱氢诃子酸甲酯和短叶苏木酚酸甲酯。体外对乙肝表面抗原（HBsAg）的抗病毒实验以及四氯化碳所致肝损伤实验表明，叶下珠具有抗乙肝病毒（HBV）的活性。
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