Yao Q Q, Zuo C X
Institute of Materia Medica, Shandong Provincial Academy of Medical Sciences, Jinan.
Yao Xue Xue Bao. 1993;28(11):829-35.
Two new phenolic compounds (crystal VI and crystal IX) have been isolated from Phyllanthus urinaria L. (Euphorbiaceae). Their structures were determined by analysis of their UV, IR, 1H-NMR, 1H-1H COSY, 13C-1H COSY, long range 13C-1H COSY, DEPT, EIMS and HREIMS spectral data. Crystal VI was determined as methyl brevifolincarboxylate. Crystal IX was elucidated as trimethyl ester dehydrochebulic acid. All of the signals of the 13C-NMR of these two new compounds have been assigned mainly according to DEPT, 13C-1H COSY and long range 13C-1H COSY. Accompanying these two new compounds, 8 known compounds have been isolated. By using chemical reactions, UV, IR, 1H-NMR, MS, their structures were elucidated as n-octadecane(I), beta-sitosterol(III), ellagic acid(IV), daucosterol(V), kaempferol(VII), quercetin(VIII), gallic acid(X) and rutin(XI). Crystal II is an aldehyde, its structure elucidation is in progress.
从叶下珠（大戟科）中分离出两种新的酚类化合物（晶体VI和晶体IX）。通过对其紫外光谱、红外光谱、1H-核磁共振、1H-1H化学位移相关谱、13C-1H化学位移相关谱、远程13C-1H化学位移相关谱、无畸变极化转移增强法、电子轰击质谱和高分辨电子轰击质谱光谱数据的分析确定了它们的结构。晶体VI被确定为短叶苏木酚酸甲酯。晶体IX被鉴定为去氢诃子三甲基酯酸。这两种新化合物的13C-核磁共振的所有信号主要根据无畸变极化转移增强法、13C-1H化学位移相关谱和远程13C-1H化学位移相关谱进行了归属。伴随着这两种新化合物，还分离出了8种已知化合物。通过化学反应、紫外光谱、红外光谱、1H-核磁共振、质谱，它们的结构被鉴定为正十八烷（I）、β-谷甾醇（III）、鞣花酸（IV）、胡萝卜苷（V）、山柰酚（VII）、槲皮素（VIII）、没食子酸（X）和芦丁（XI）。晶体II是一种醛，其结构鉴定正在进行中。
