Li M G, Nilsson K G
Implant Research Unit, Department of Orthopaedics, University Hospital, Umeå, Sweden.
J Arthroplasty. 2001 Oct;16(7):893-900. doi: 10.1054/arth.2001.24376.
The relationship between changes in bone mineral density (BMD) in the proximal tibia and fixation of the tibial component during 2 years postoperatively was investigated in 28 knees. BMD was measured using dual-energy x-ray absorptiometry, and fixation was determined using radiostereometric analysis. BMD decreased at 3 months and returned to baseline level at 24 months, but with large variations on an individual basis. Most of the prosthetic migration occurred within the initial 3 months. The results show that the bone remodeling that occurs during the 2 years after operation has no relation to the migration of the tibial component. The early migration seems to be related more to local activities at the interface rather than to changes in BMD assessed below the interface. The changes in BMD during 2 years reflect the bone remodeling caused by the normalization of alignment after operation and are not related to the implant fixation.
对28个膝关节进行研究，以探讨术后2年内胫骨近端骨密度（BMD）变化与胫骨部件固定之间的关系。采用双能X线吸收法测量骨密度，并通过放射立体测量分析确定固定情况。骨密度在术后3个月下降，并在24个月时恢复到基线水平，但个体差异较大。大多数假体移位发生在术后最初3个月内。结果表明，术后2年内发生的骨重塑与胫骨部件的移位无关。早期移位似乎更多地与界面处的局部活动有关，而非与界面以下评估的骨密度变化有关。2年内骨密度的变化反映了术后对线正常化引起的骨重塑，与植入物固定无关。
