Rodriguez de Romo A C, Borgstein J
National Autonomous University of Mexico.
Vesalius. 1999 Jun;5(1):18-24.
In 1848, Claude Bernard described the lipolytic function of the pancreas. His experimental procedure was original and as he always affirmed, easily replicable. In this study we repeated the original Bernardian experiments for emulsification and saponification of fats, following the original descriptions from his laboratory manuscripts. The results were astonishingly similar to those obtained by Bernard, confirming the validity of his experiments and conclusions, as well as emphasising again his original concepts on the importance of experimental repeatability in scientific medicine. Considering the surgical difficulties we encountered, we must conclude that Claude Bernard required great manual dexterity to obtain these results without the benefit of modern technology and anaesthesia.
1848年，克劳德·伯纳德描述了胰腺的脂解功能。他的实验方法很新颖，而且正如他一直所宣称的，很容易复制。在本研究中，我们按照他实验室手稿中的原始描述，重复了伯纳德关于脂肪乳化和皂化的原始实验。结果与伯纳德所获得的结果惊人地相似，这证实了他的实验和结论的有效性，同时也再次强调了他关于科学医学中实验可重复性重要性的原始概念。考虑到我们遇到的手术困难，我们必须得出结论，克劳德·伯纳德在没有现代技术和麻醉的情况下获得这些结果需要极高的手工灵巧性。
