Wolf R L, Spitz L, Levin S E, Isdale J
S Afr Med J. 1975 Aug 23;49(36):1477-80.
The clinical features of a 9-year-old boy with an extra-adrenal phaeochromocytoma, complicated by malignant hypertension, are described. The value of urinary and blood catecholamine assays and specialised radiological investigations in the accurate localisation of the tumour, is emphasised. Successful removal of the tumour was facilitated by pre-operative control of the hypertension with a combination of alpha and beta-adrenergic blockade (phenoxybenzamine and practolol). Intra-operative control of fluctuations in blood pressure was simplified by the use of Ethrane (enflurane compound 347) as one of the anaesthetic agents. As a result, sodium nitroprusside was infrequently used.
本文描述了一名9岁男孩患有肾上腺外嗜铬细胞瘤并伴有恶性高血压的临床特征。强调了尿和血儿茶酚胺测定以及专门的放射学检查在肿瘤精确定位中的价值。术前联合使用α和β肾上腺素能阻滞剂（苯氧苄胺和心得宁）控制高血压，为成功切除肿瘤提供了便利。术中使用恩氟烷（安氟醚化合物347）作为麻醉剂之一，简化了血压波动的控制。因此，硝普钠的使用频率较低。
