Cordes U, Georgi M, Günther R, Beyer J
Dtsch Med Wochenschr. 1979 Mar 2;104(9):317-23. doi: 10.1055/s-0028-1103904.
Urinary catecholamines and urinary excretion of vanillylmandelic acid confirmed the diagnosis of phaeochromocytoma in ten patients. In two of seven a modified glucagon test significantly aided confirmation of the diagnosis. In all patients the tumour was localised both by catecholamine determination in blood from the vein draining into the inferior vena cava (IVC) and by adrenal phlebography. Site of the adrenal tumour was definitively determined by the high catecholamine level in the adrenal veins and by phlebography. Three extra-adrenal tumours, a thoracic and two abdominal ones, were localised by high catecholamine levels in blood from other veins draining into the IVC. Vanillylmandelic acid determinaion was unreliable in the diagnosis of small phaeochromocytomas.
尿儿茶酚胺和香草扁桃酸的尿排泄量证实了10例患者患有嗜铬细胞瘤。在7例患者中的2例,改良胰高血糖素试验对确诊有显著帮助。在所有患者中,通过测定引流至下腔静脉(IVC)的静脉血中的儿茶酚胺以及肾上腺静脉造影来定位肿瘤。肾上腺肿瘤的位置通过肾上腺静脉中的高儿茶酚胺水平和静脉造影得以明确确定。3例肾上腺外肿瘤,1例位于胸部,2例位于腹部,通过引流至IVC的其他静脉血中的高儿茶酚胺水平得以定位。香草扁桃酸测定在小嗜铬细胞瘤的诊断中不可靠。