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犬短暂失血性低血压后的再输血酸中毒

Retransfusion acidosis after brief haemorrhagic hypotension in the dog.

作者信息

Takács L, Szántó G, Vándor E

出版信息

Acta Chir Acad Sci Hung. 1976;17(2):161-7.

PMID:11626
Abstract

Dogs under chloralose anasthesia were bled at a rate of 50 ml/min to a total of 25 ml/kg body weight and 2 minutes later a quick reinfusion of adequate volumes of blood, dextran, or Locke's solution was done. Within 2 minutes after reinfusion, the pH of arterial blood fell by 0.074--0.127; concurrently, PaCO2 rose by 9.2-12.9 mm Hg. A close correlation was demonstrated between these changes. After retransfusion, PaO2 and the arterial lactic acid level did not change significantly. Thus retransfusion acidosis in the dog appears after a brief hypotensive period, too, but cannot be attributed to a "washout" of lactate from the tissues.

摘要

在水合氯醛麻醉下的狗以每分钟50毫升的速度放血,放血量总计为每千克体重25毫升,两分钟后快速回输适量的血液、右旋糖酐或洛克氏溶液。回输后两分钟内,动脉血pH值下降了0.074 - 0.127;同时,动脉血二氧化碳分压上升了9.2 - 12.9毫米汞柱。这些变化之间显示出密切的相关性。再输血后,动脉血氧分压和动脉乳酸水平没有显著变化。因此,狗的再输血酸中毒在短暂的低血压期后也会出现,但不能归因于组织中乳酸的“冲洗”。

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