Gennari L, Doci R, Podrecca S, Orefice S, Bozzetti F, Cataldo I
Tumori. 1975 May-Jun;61(3):237-47. doi: 10.1177/030089167506100302.
127 anterior resections for adenocarcinoma of the rectum and sigmoid were performed at the Istituto Nazionale Tumori from 1950 to 1972. In 48% of cases the site of tumor was upper rectum and recto-sigmoid. The surgical mortality rate was 4,7%. Complications were observed in about 40%, fecal fistula being the most frequent. It seems correlable with the anastomotic technique and is significantly reduced by colostomy. Local failure occurred in 8,3% of patients with maximum rate (28,5%) for tumors located under 12 cm from the anus. The 5-year over-all survival rate was 73,3% with substantial differences according to the extent in initial disease.
1950年至1972年期间,意大利国立肿瘤研究所对127例直肠和乙状结肠腺癌患者进行了前切除术。48%的病例中肿瘤位于直肠上段和直肠乙状结肠交界处。手术死亡率为4.7%。约40%的患者出现并发症,其中粪瘘最为常见。这似乎与吻合技术有关,结肠造口术可显著降低其发生率。距肛门12厘米以下的肿瘤局部复发率最高(28.5%),8.3%的患者出现局部复发。5年总生存率为73.3%,根据初始疾病的程度存在显著差异。