Halberg G P, Kelly S E, Morrone M
Ann Ophthalmol. 1975 Sep;7(9):1199-1204, 1207-9.
Two new topical ophthalmic delivery systems are described. The modes of delivery were compared with conventionally administered eyedrops on the basis of intraocular pressure lowering effect, dependability in delivery of prescribed dosage, and patient acceptance of the system. Pilocarpine delivered by each of the systems was found to control IOP as well as conventional pilocarpine drops. Although some patients took a longer time than others to adjust to a new mode of delivery, patient acceptance of the systems was high.
描述了两种新型局部眼部给药系统。基于降低眼压的效果、规定剂量给药的可靠性以及患者对该系统的接受度,将这两种给药方式与传统给药眼药水进行了比较。发现通过每种系统递送的毛果芸香碱在控制眼压方面与传统毛果芸香碱滴眼液效果相同。尽管有些患者比其他患者需要更长时间来适应新的给药方式,但患者对这些系统的接受度很高。