Bensinger R, Shin D H, Kass M A, Podos S M, Becker B
Invest Ophthalmol. 1976 Dec;15(12):1008-10.
Pilocarpine was administered to a selected group of ocular hypertensive subjects in the form of a synthetic biosoluble matrix inserted into the conjunctival cul-de-sac. Satisfactory lowering of the intraocular pressure resulted, with a minimum of subject intolerance. The decreased pressure response was significant in some cases for greater than 24 hours. Drug delivery by soluble inserts offers promise as a convenient and effective mode of therapy.
毛果芸香碱以插入结膜穹窿的合成生物可溶基质的形式给予一组选定的高眼压受试者。眼压得到了令人满意的降低，受试者的不耐受情况降至最低。在某些情况下，眼压降低反应在超过24小时内都很显著。通过可溶性植入物给药有望成为一种方便有效的治疗方式。
