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是什么塑造了疫苗政策?以英国的乙型肝炎为例。

What shapes vaccine policy? The case of hepatitis B in the UK.

作者信息

Stanton J

机构信息

London School of Hygiene and Tropical Medicine.

出版信息

Soc Hist Med. 1994 Dec;7(3):427-46. doi: 10.1093/shm/7.3.427.

Abstract

Comparison of hepatitis B vaccine policy with other cases in the past is complicated by the restricted modes of transmission of this disease, which affects relatively few people in the UK. Still, considerations of cost, fear of contamination, divisions of opinion within the medical profession, and regional dispersal of authority are all factors--analysed for other vaccines--which help to explain the limited UK central policy on hepatitis B immunization observed through the 1980s. An important issue, in previous debates on vaccine policies, has been the conflict between public health interests and the rights of individuals to eschew health interventions imposed by the state. It is argued here that this question fed into hepatitis B vaccine policy in an oblique manner, via policy on screening for hepatitis B in the 1970s; minimal screening mainly of selected groups of health workers was favoured, maximizing individual rights. Changes to hepatitis B vaccine policy can be traced, linked with international policy, pharmaceutical company pressure, advances in vaccine technology, and questions of legal liability. The most accurate predictor for vaccine policy appears to have been screening policy. Will this apply to AIDS, which is epidemiologically similar to hepatitis B?

摘要

将乙肝疫苗政策与过去的其他案例进行比较是复杂的,因为这种疾病的传播方式有限,在英国受影响的人数相对较少。尽管如此,成本因素、对污染的担忧、医学界内部的意见分歧以及权力的地区分散,这些在分析其他疫苗时所考虑的因素,都有助于解释20世纪80年代英国在乙肝免疫方面中央政策有限的情况。在以往关于疫苗政策的辩论中,一个重要问题是公共卫生利益与个人规避国家强制实施的健康干预措施的权利之间的冲突。本文认为,这个问题以一种间接的方式影响了乙肝疫苗政策,是通过20世纪70年代的乙肝筛查政策;当时倾向于主要对选定的医护人员群体进行最小化筛查,以最大化个人权利。乙肝疫苗政策的变化可以追溯到与国际政策、制药公司的压力、疫苗技术的进步以及法律责任问题有关。疫苗政策最准确的预测因素似乎一直是筛查政策。这是否适用于在流行病学上与乙肝相似的艾滋病呢?

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