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[日本药局方(JP)中精神药物的变迁(第3部分)。JP I(1886年)至JP V(1932年)期间缬草根的标准和检测方法的变迁以及与美国药典(USP)和英国药典(BP)的比较]

[The transition of psychotropic drugs in Japanese pharmacopoeia (JP) (Part 3). The transition of the standards and the testmethods of valerianae radix between JP I (1886) and JP V (1932) and the comparison with USP and BP].

作者信息

Yanagisawa K

机构信息

The Japanese Society of History of Pharmacy.

出版信息

Yakushigaku Zasshi. 1992;27(1):40-9.

Abstract

This is the study on the transition of the standards and test-methods for valerianae radix as a sedative between JP I (1886) and JP V (1932), and the study on the comparison with the same generation of USP and BP. The results were as follows: 1) Valerianae radix was the vegetable drugs originally produced in Europe. The government always studied the vegetable drugs produced in Japan, as the substitute to one produced in Europe. The government provided the drugs newly produced in Japan for valerianae radix in JP II (1891). The study gave a good result to the market when World War I began. That is to say, Japanese valerianae transferred to the true position from the substitute in JP IV (1920). 2) The test-methods of judgment for valerianae radix were based on the form between JP I and JP V mainly. The technical level of judgment was equal to USP and BP. The methods were the standard of judgment for the vegetable drugs to maintain quality in those days.

摘要

这是一项关于缬草根作为镇静剂在《日本药局方》第一版(1886年)和第五版(1932年)之间标准及检验方法转变的研究,以及与同一时期美国药典和英国药典的比较研究。结果如下:1)缬草根是原产于欧洲的植物药。日本政府一直研究日本产的植物药,作为欧洲产植物药的替代品。在《日本药局方》第二版(1891年)中,政府将日本新生产的药品用于缬草根。第一次世界大战开始时,该研究在市场上取得了良好效果。也就是说,日本缬草根在《日本药局方》第四版(1920年)中从替代品转变为正品。2)缬草根的判定检验方法主要基于《日本药局方》第一版和第五版之间的形式。判定技术水平与美国药典和英国药典相当。这些方法是当时植物药保持质量的判定标准。

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