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[法国首款尿路血管造影用碘化水溶性产品Tenebryl的发现]

[The discovery of Tenebryl, the first French uro-angiographic iodized hydrosoluble product].

作者信息

Bonnemain B, Guerbet M

出版信息

Rev Hist Pharm (Paris). 1995;42(306 Suppl):279-84.

Abstract

Ténébryl was perfected in 1931 by Marcel and André Guerbet. For the company which bore their name and after the discovery of Lipiodol, this was the opportunity to explore a new area in radiology: intravenous urography. The discovery of this product is exemplary in a greater sense, since it contributed to opening the way to a new class of contrast products of which the majority today are iodized products. All the ingredients of industrial research are present here, from risk-taking to successful commercialization.

摘要

1931年,马塞尔(Marcel)和安德烈·盖尔贝(André Guerbet)完善了Ténébryl。对于以他们名字命名的公司以及在发现碘油之后,这是探索放射学新领域——静脉尿路造影术的契机。从更广泛的意义上讲,这种产品的发现堪称典范,因为它为一类新的造影剂产品开辟了道路,如今这类产品大多数都是含碘产品。从冒险到成功商业化,工业研究的所有要素都体现在这里。

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