Bonnemain B, Guerbet M
Rev Hist Pharm (Paris). 1995;42(305):159-70.
The history of Lipiodol, an iodized oil perfected in 1901 by Marcel Guerbet and Laurent Lafay, offers the example of a product with multiple indications which, initially destined for therapeutic usage, was later successfully turned to radiologic applications; then, sixty years later, returned to its initial purposes. This shows that (1) very often new products find usages which their developers never suspected; (2) research can extend beyond the original synthesis and commercialization of the product; (3) at some point research on a medication becomes multidisciplinary.
1901年由马塞尔·盖尔贝和洛朗·拉法伊完善的碘化油“碘油”的历史，为一种具有多种适应症的产品提供了范例。该产品最初用于治疗用途，后来成功转向放射学应用；然后，六十年后，又回归到其最初的用途。这表明：（1）新产品常常会找到其开发者从未预料到的用途；（2）研究可以超越产品最初的合成和商业化；（3）在某个时候，对一种药物的研究就会变得多学科化。
