Swenson O, Sherman J O, Fisher J H, Cohen E
Ann Surg. 1975 Sep;182(3):266-73. doi: 10.1097/00000658-197509000-00008.
In 1948 one of us (O.S.) proposed a new method of treatment, abdominoperineal resection, for patients with congential megacolon. Since then, 483 patients have been treated by 13 pediatric surgeons in Chicago and Boston using this technique. Two hundred and eight-two of the patients were last interviewed and examined more than 5 years after the resection. There were 16 postoperative deaths (3.3%) and 6 late deaths (1.2%) from enterocolitis. Both early and late complications were infrequent and are discussed in detail. Almost 90% of the patients reported that they now have normal bowel habits. None of the patients developed urinary incontinence or impotence, although ten patients (2.1%) reported permanent fecal soiling. This is the first large group of patients treated for congenital megacolon who have been followed to adulthood. The low incidence of postoperative complications and minimal frequency of long-term complications indicate that the abdominoperineal resection is a safe, effective method of treatment for congenital megacolon.
1948年，我们中的一人（O.S.）提出了一种针对先天性巨结肠患者的新治疗方法——腹会阴切除术。从那时起，芝加哥和波士顿的13位儿科外科医生使用该技术治疗了483名患者。其中282名患者在切除术后5年多接受了最后一次访谈和检查。术后有16例死亡（3.3%），6例因小肠结肠炎导致的晚期死亡（1.2%）。早期和晚期并发症都不常见，并将进行详细讨论。近90%的患者报告称他们现在排便习惯正常。没有患者出现尿失禁或阳痿，不过有10名患者（2.1%）报告有永久性粪便污染。这是第一组接受先天性巨结肠治疗并随访至成年的大量患者。术后并发症发生率低，长期并发症发生频率低，表明腹会阴切除术是治疗先天性巨结肠的一种安全、有效的方法。
