Galperin C
Université Charles de Gaulle, Centre de recherche sur l'analyse et la théorie des savoirs, Lille, France.
Rev Hist Sci Paris. 1994 Jan-Mar;47(1):7-56. doi: 10.3406/rhs.1994.1189.
Our purpose here is to retrace the history of the concept of prophage, to show how it expands into that of the episome and provirus. Its prehistory is that of lysogeny. We stress the relations between heredity and infection, the discovery of a non infectioius phase of the phage. André Lwoff is responsible for the concept of prophage. We then examine the research, discoveries and interpretations of François Jacob, Elie Wollman, William Hayes and Joshua Lederberg.
我们在此的目的是追溯原噬菌体概念的历史，展示它是如何扩展为附加体和前病毒概念的。它的史前史就是溶源性的历史。我们强调遗传与感染之间的关系，以及噬菌体非感染阶段的发现。安德烈·利沃夫提出了原噬菌体的概念。然后我们考察弗朗索瓦·雅各布、伊利·沃尔曼、威廉·海斯和乔舒亚·莱德伯格的研究、发现及阐释。
