Chruściel T L
Int J Clin Pharmacol Biopharm. 1975 Jul;12(1-2):57-62.
Rapid increase in our knowledge of acute biological effects of cannabis and its biologically active components is contrasted with the slow rate of progress achieved in the area of effects of long-term use of cannabis in man. Such studies belong to the difficult category of long-term clinical pharmacological studies, that are time-consuming, require large population samples, and considerable expertise of staff. Recently published epidemiological studies on effects of long-term cannabis use, although still not yet conclusive, supply increasing evidence of harmful effects of such use. Recently, the World Health Organization has sponsored several research projects of this nature in countries with easy access to long-term heavy cannabis users.
我们对大麻及其生物活性成分的急性生物学效应的了解迅速增加，与之形成对比的是，在长期使用大麻对人体影响这一领域所取得的进展缓慢。这类研究属于长期临床药理学研究的困难范畴，既耗时，又需要大量的人群样本以及工作人员具备相当的专业知识。最近发表的关于长期使用大麻影响的流行病学研究，虽然尚无定论，但越来越多地证明了这种使用方式的有害影响。最近，世界卫生组织在那些容易接触到长期重度大麻使用者的国家资助了几个此类研究项目。
