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Ethics and statistics in randomized clinical trials.

作者信息

Royall Richard M, Bartlett Robert H, Cornell Richard G, Byar David P, Dupont William D, Levine Robert J, Lindley Foster, Simes R John, Zelen M

出版信息

Stat Sci. 1991;6(1):52-88. doi: 10.1214/ss/1177011934.

DOI:10.1214/ss/1177011934

PMID:11653993

Abstract

摘要

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Ethics and statistics in randomized clinical trials.

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Ethics and statistics in randomized clinical trials.

作者信息

Royall Richard M, Bartlett Robert H, Cornell Richard G, Byar David P, Dupont William D, Levine Robert J, Lindley Foster, Simes R John, Zelen M

出版信息

Stat Sci. 1991;6(1):52-88. doi: 10.1214/ss/1177011934.

DOI:10.1214/ss/1177011934

PMID:11653993

Abstract

摘要

相似文献

Ethics and statistics in randomized clinical trials.

Stat Sci. 1991;6(1):52-88. doi: 10.1214/ss/1177011934.

Balancing moral principles in federal regulations on human research.

IRB. 1992 Jan-Feb;14(1):1-6.

The changing doctor-patient relationship and the new medical ethics.

SA J Contin Med Educ. 1987 Apr;5(4):27, 29, 32-34.

Autonomy, beneficence, and the experimental subject's consent: a response to Jay Katz.

St Louis Univ Law J. 1993 Fall;38(1):55-62.

Human experimentation and human rights.

St Louis Univ Law J. 1993 Fall;38(1):7-54.

Child development and research ethics: a changing calculus of concerns.

Bus Prof Ethics J. 1990;9(1 and 2):193-206. doi: 10.5840/bpej199091/23.

Does the moral philosophy of the Belmont Report rest on a mistake?

IRB. 1986 Nov-Dec;8(6):5-6.

The evolution of informed consent in American medicine.

Perspect Biol Med. 1995 Spring;38(3):498-510. doi: 10.1353/pbm.1995.0039.

Patient choices, family interests, and physician obligations.

Kennedy Inst Ethics J. 1994 Mar;4(1):27-46. doi: 10.1353/ken.0.0065.

Research with human subjects.

Hastings Cent Rep. 1988 Oct-Nov;18(5):47-9.

引用本文的文献

Adaptive treatment allocation and selection in multi-arm clinical trials: a Bayesian perspective.

BMC Med Res Methodol. 2022 Feb 20;22(1):50. doi: 10.1186/s12874-022-01526-8.

Outcome-adaptive randomization in clinical trials: issues of participant welfare and autonomy.

Theor Med Bioeth. 2019 Apr;40(2):83-101. doi: 10.1007/s11017-019-09481-0.

Are adaptive randomised trials or non-randomised studies the best way to address the Ebola outbreak in west Africa?

Lancet Infect Dis. 2015 Jun;15(6):738-45. doi: 10.1016/S1473-3099(15)70106-4. Epub 2015 Apr 14.

Challenges of clinical trial design when there is lack of clinical equipoise: use of a response-conditional crossover design.

J Neurol. 2012 Feb;259(2):348-52. doi: 10.1007/s00415-011-6200-0. Epub 2011 Aug 7.

The epistemology and ethics of chronic disease research: further lessons from ECMO.

Theor Med Bioeth. 2010 Apr;31(2):107-22. doi: 10.1007/s11017-010-9139-8.

Statistics and ethics: models for strengthening protection of human subjects in clinical research.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22037-8. doi: 10.1073/pnas.0912882107. Epub 2009 Dec 22.

Bandit solutions provide unified ethical models for randomized clinical trials and comparative effectiveness research.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22387-92. doi: 10.1073/pnas.0912378106. Epub 2009 Dec 14.

Adaptive designs for randomized trials in public health.

Annu Rev Public Health. 2009;30:1-25. doi: 10.1146/annurev.publhealth.031308.100223.

Practical Bayesian adaptive randomisation in clinical trials.

Eur J Cancer. 2007 Mar;43(5):859-66. doi: 10.1016/j.ejca.2007.01.006. Epub 2007 Feb 16.

Ethical problems of evaluating a new treatment for melioidosis.

BMJ. 2003 Nov 29;327(7426):1280-2. doi: 10.1136/bmj.327.7426.1280.

Ethics and statistics in randomized clinical trials.

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Ethics and statistics in randomized clinical trials.

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