Welsh Kathleen A, Ballard Edna, Nash Florence, Raiford Kate, Harrell Lindy
Bryan Alzheimer's Disease Research Center, Duke University Medical Center, Durham, North Carolina 27705.
Alzheimer Dis Assoc Disord. 1994;8(Suppl. 4):38-48.
Despite the need for minority subjects in research studies of Alzheimer disease (AD), the successful involvement of minority patients in such studies has been difficult. This report discusses the many societal, economic, logistical, and attitudinal barriers that have inhibited the participation of minority patients and their families in medical research programs of AD. Special consideration is given to the unique cultural issues that arise when conducting studies involving African-American elderly subjects. Methods are considered for overcoming the barriers to participation gleaned from the national study CERAD (Consortium to Establish a Registry of Alzheimer Disease) and other investigations of AD. Recommendations are made for future research programs targeted on the specific health care needs and concerns of the minority segments of our population.
尽管在阿尔茨海默病（AD）研究中需要少数族裔受试者，但少数族裔患者成功参与此类研究却很困难。本报告讨论了诸多社会、经济、后勤和态度方面的障碍，这些障碍阻碍了少数族裔患者及其家庭参与AD医学研究项目。特别考虑了在开展涉及非裔美国老年受试者的研究时出现的独特文化问题。探讨了从全国性研究CERAD（建立阿尔茨海默病登记处联盟）及其他AD调查中收集到的克服参与障碍的方法。针对以我国少数族裔人群的特定医疗保健需求和关切为目标的未来研究项目提出了建议。
