Mnich Z
Acta Otolaryngol. 1975 Jul-Aug;80(1-2):111-5. doi: 10.3109/00016487509121308.
The efflux of Na-24 was investigated in isolated labyrinths from a membrane section containing stria vascularis and spiral ligament in artificial endolymph medium. The efflux curves were calculated and compartmental analyses were made. The theoretical possibility of a exchange of sodium between compartments connected in different ways was considered. The calculated values of rate constant of transmembranal sodium fluxes are 0.0282+/-0.0052 min-1 and the half-time of the exchange of sodium between intracellular compartments is 24.27+/-4.53 min. The distribution of sodium in tissue with a commonly applied simplification gives 90% Na+ in the extracellular compartment and 3% Na+ in the intracellular compartment of the total tissue sodium content. The possibility of measuring the rate constant of transmembranal electrolyte fluxes in this tissue seems encouraging for future investigation of the mechanism by which they are transported.
在人工内淋巴介质中，从包含血管纹和螺旋韧带的膜切片分离出的迷路中研究了Na-24的流出情况。计算了流出曲线并进行了房室分析。考虑了以不同方式连接的房室之间钠交换的理论可能性。跨膜钠通量速率常数的计算值为0.0282±0.0052 min-1，细胞内房室之间钠交换的半衰期为24.27±4.53 min。按照常用的简化方法，组织中钠的分布为：在细胞外房室中占总组织钠含量的90%，在细胞内房室中占3%。测量该组织中跨膜电解质通量速率常数的可能性，似乎为未来研究它们的转运机制带来了希望。
