Fix M K, Manser P, Born E J, Vetterli D, Mini R, Rüegsegger P
Institute for Biomedical Engineering, University of Zurich and ETH.
Z Med Phys. 2001;11(3):163-70. doi: 10.1016/s0939-3889(15)70508-8.
Study of behavior and influence of a multileaf collimator (MLC) on dose calculation, verification, and portal energy spectra in the case of intensity-modulated fields obtained with a step-and-shoot or a dynamic technique.
The 80-leaf MLC for the Varian Clinac 2300 C/D was implemented in a previously developed Monte Carlo (MC) based multiple source model (MSM) for a 6 MV photon beam. Using this model and the MC program GEANT, dose distributions, energy fluence maps and energy spectra at different portal planes were calculated for three different MLC applications.
The comparison of MC-calculated dose distributions in the phantom and portal plane, with those measured with films showed an agreement within 3% and 1.5 mm for all cases studied. The deviations mainly occur in the extremes of the intensity modulation. The MC method allows to investigate, among other aspects, dose components, energy fluence maps, tongue-and-groove effects and energy spectra at portal planes.
The MSM together with the implementation of the MLC is appropriate for a number of investigations in intensity-modulated radiation therapy (IMRT).
研究多叶准直器(MLC)在采用步进-射野或动态技术获得的调强射野情况下对剂量计算、验证及射野能谱的影响及其行为。
在先前开发的基于蒙特卡罗(MC)的6 MV光子束多源模型(MSM)中,为Varian Clinac 2300 C/D配备了80叶MLC。利用该模型和MC程序GEANT,针对三种不同的MLC应用,计算了不同射野平面处的剂量分布、能注量图和能谱。
将模体和射野平面中MC计算的剂量分布与胶片测量的剂量分布进行比较,结果表明,在所研究的所有情况下,二者在3%和1.5 mm范围内一致。偏差主要出现在调强的极值处。MC方法可用于研究射野平面处的剂量分量、能注量图、舌槽效应和能谱等诸多方面。
MSM与MLC的结合适用于调强放射治疗(IMRT)中的多项研究。