Alexander K P, Peterson E D
Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC, USA.
Am J Manag Care. 2001 Oct;7(10):951-6.
Women and men with coronary artery disease (CAD) differ in their presenting symptoms, baseline risk factors, age, and body size. These differences account for most of the previously reported differences in the management of women with CAD. When using larger databases and adjusting for confounding factors, women increasingly resemble men in terms of the care they receive and their outcomes. We reviewed recent articles on the pharmacologic and surgical management of women with CAD. Although women and men with CAD should be treated similarly, physicians still must recognize the sometimes atypical presentation of CAD in women and be mindful of the smaller body size of women regarding drug dosing and revascularization.
患有冠状动脉疾病(CAD)的女性和男性在症状表现、基线风险因素、年龄和体型方面存在差异。这些差异是先前报道的CAD女性患者管理差异的主要原因。当使用更大的数据库并对混杂因素进行调整时,女性在接受的治疗及其结果方面越来越类似于男性。我们回顾了近期关于CAD女性患者药物和手术治疗的文章。尽管CAD女性和男性患者应接受相似的治疗,但医生仍必须认识到CAD在女性中有时会有非典型表现,并在药物剂量和血运重建方面注意女性体型较小的情况。