Woods J E, Chong G C, Beahrs O H
Am J Surg. 1975 Oct;130(4):460-2. doi: 10.1016/0002-9610(75)90484-5.
Experience with 1,360 primary parotid tumors seen at the Mayo Clinic during two fifteen year periods, 1940 through 1954 and 1955 through 1969, is reviewed. A comparison of histopathologic classification, type of treatment indicated, recurrence rates, and survival in the two periods reveals considerably greater understanding of all factors in the later fifteen year period. The relatively high mortality still encountered among patients with high grade malignant tumors of the parotid glands indicate the nature of the challenge still to be met. Based on the data in this study, it is our opinion that superficial or total conservative parotidectomy is best employed primarily for benign tumors and that the shift to more radical operative procedures should continue in the management of malignant tumors, especially those that are less well differentiated. For experienced surgeons, exceptions might be the small superficially located tumors or the tumors in the lower pole of the gland such as Warthin's tumors. Local excision with removal of a margin of parotid parenchyma might be justifiable in such cases.
回顾了梅奥诊所(Mayo Clinic)在两个十五年期间(1940年至1954年以及1955年至1969年)所诊治的1360例原发性腮腺肿瘤的经验。对这两个时期的组织病理学分类、建议的治疗类型、复发率及生存率进行比较后发现,在第二个十五年期间对所有因素有了更深入的了解。腮腺高级别恶性肿瘤患者中仍存在相对较高的死亡率,这表明仍需应对的挑战的性质。基于本研究中的数据,我们认为,浅叶或全腮腺保守切除术主要适用于良性肿瘤,而在恶性肿瘤的治疗中,尤其是那些分化较差的肿瘤,应继续转向更激进的手术方式。对于经验丰富的外科医生而言,位于浅部的小肿瘤或腺体内下极的肿瘤(如沃辛瘤)可能为例外。在此类情况下,切除腮腺实质边缘的局部切除术可能是合理的。