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腮腺多形性腺瘤:包膜外剥离术与腮腺浅叶切除术的比较——一项10年回顾性队列研究

Pleomorphic adenoma of the parotid: extracapsular dissection compared with superficial parotidectomy--a 10-year retrospective cohort study.

作者信息

Cristofaro Maria Giulia, Allegra Eugenia, Giudice Amerigo, Colangeli Walter, Caruso Davide, Barca Ida, Giudice Mario

机构信息

Department of Oral and Maxillofacial Surgery, UMG of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.

Department of Otolaryngology, UMG of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.

出版信息

ScientificWorldJournal. 2014;2014:564053. doi: 10.1155/2014/564053. Epub 2014 Oct 21.

Abstract

The purpose of this study was to investigate the complication rates and effectiveness of extracapsular dissection compared with superficial parotidectomy for pleomorphic adenomas of the parotid gland from 2002 to 2012. The authors carried out a retrospective cohort study of 198 patients with pleomorphic adenomas of the parotid gland. Extracapsular dissection (ED) or superficial parotidectomy (SP) was performed. The recurrence rate and complications of the two surgical techniques were measured with a univariate analysis of each variable using the appropriate statistical analysis (chi-squared test or t-test). A total of 198 patients were enrolled between January 2003 and December 2012. The study included 97 females (48.99%) and 101 males (51.01%) whose mean age was 50.97 years (range 14-75). The type of surgery performed was ED in 153 patients (77.27%, 80 males and 73 females) and SP in 45 patients (22.73%, 21 males and 24 females). The mean follow-up time was 61.02 +/- 4.9 months for the patients treated with ED and 66.4 +/- 4.5 months for the patients treated with SP. Transient facial nerve injury and facial paralysis were significantly more frequent after SP than after ED (P = 0.001 and P = 0.065, resp.). No significant differences in capsular rupture, recurrence, and salivary fistula were observed after SP or ED: 2.2% versus 3.9%, 2.2% versus 3.3%, and 2.2% versus 0.65%, respectively. Extracapsular dissection may be considered the treatment of choice for pleomorphic adenomas located in the superficial portion of the parotid gland because this technique showed similar effectiveness and fewer side effects than superficial parotidectomy.

摘要

本研究的目的是调查2002年至2012年期间,与腮腺浅叶切除术相比,腮腺多形性腺瘤行包膜外剥离术的并发症发生率及有效性。作者对198例腮腺多形性腺瘤患者进行了一项回顾性队列研究。实施了包膜外剥离术(ED)或腮腺浅叶切除术(SP)。采用适当的统计分析(卡方检验或t检验)对每个变量进行单因素分析,以测量两种手术技术的复发率和并发症。2003年1月至2012年12月期间共纳入198例患者。该研究包括97名女性(48.99%)和101名男性(51.01%),平均年龄为50.97岁(范围14 - 75岁)。接受手术的类型为153例患者行ED(77.27%,80例男性和73例女性),45例患者行SP(22.73%,21例男性和24例女性)。接受ED治疗的患者平均随访时间为61.02±4.9个月,接受SP治疗的患者平均随访时间为66.4±4.5个月。SP术后短暂性面神经损伤和面瘫的发生率明显高于ED(分别为P = 0.001和P = 0.065)。SP或ED术后在包膜破裂、复发和涎瘘方面未观察到显著差异:分别为2.2%对3.9%、2.2%对3.3%和2.2%对0.65%。包膜外剥离术可被视为位于腮腺浅部的多形性腺瘤的首选治疗方法,因为该技术显示出与腮腺浅叶切除术相似的有效性且副作用更少。

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