Ng P P, Phatouros C C, Khangure M S
Department of Diagnostic and Interventional Radiology, Royal Perth Hospital, Western Australia.
AJNR Am J Neuroradiol. 2001 Oct;22(9):1761-3.
Thrombotic occlusion of the anterior communicating and right anterior cerebral arteries occurred during embolization of an acutely ruptured aneurysm of the anterior communicating artery. Traditional management, including superselective infusion of a fibrinolytic agent, was unsuccessful in reestablishing normal vessel patency. Therefore, an intravenous dose of abciximab was administered. Serial angiography showed that normal vessel patency was reestablished within 10 min. There were no adverse events related to abciximab administration, and the patient recovered from the procedure without neurologic deficit.
前交通动脉急性破裂动脉瘤栓塞过程中发生了前交通动脉和右侧大脑前动脉的血栓闭塞。包括超选择性注入纤维蛋白溶解剂在内的传统治疗方法未能成功恢复正常血管通畅。因此，给予了静脉注射阿昔单抗剂量。连续血管造影显示在10分钟内恢复了正常血管通畅。没有与阿昔单抗给药相关的不良事件，患者术后恢复且无神经功能缺损。
